Any significant deterioration in graft function should be investigated using the appropriate diagnostic tools and, if possible, therapeutic interventions should be initiated. The usual causes of a decline in glomerular filtration rate after the first year include:
Causes related to allograft includes:
- Chronic allograft rejection
- Acute rejection
- Transplant renal artery stenosis
- Ureteric obstruction
- Recurrent and De novo glomerlonephritis
- BK virus nephropathy
- Calcineurin induced nephropathy
Causes not related to allograft includes:
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