Saturday, February 20, 2010

The Solitary Pulmonary Nodule

A solitary pulmonary nodule or coin lesion is an approximately round lesion that is less than 3 cm in diameter and that is completely surrounded by pulmonary parenchyma without other abnormalities.
Lesions larger than 3 cm are called masses and are often malignant.

Pulmonary nodules are usually discovered incidentally on CXR but CT scan is considered the required standard.

Radiographic features distinguishing benign and malignant:

Margins - two pattern of margin are relatively specific for cancer.
  • Corona radiata/ spiculated appearance - very fine linear strands extending 4 - 5 mm outward from the nodule.
  • Scalloped border - associated with intermediate probability of cancer.
Calcification - suggest it is a benign lesion.
  • laminated or central pattern is typical of granuloma.
  • popcorn pattern is seen in harmartomas.
Growth rate - the volume-dobuling time for malignant bronchogenic tumours is rarely less than a month or more than a year.

If the lesion is spherical, a 30 percent increase in diameter represents a doubling of volume.


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